Derek Tan

Derek Tan

Company: Memorial Sloan Kettering Cancer Center

Job title: Member, Tri-institutional Professor, Chair, Chemical Biology Program


SEAKERs: Targeted Cellular Micropharmacies that Generate Small- Molecule Drugs in situ 4:30 pm

SEAKER (Synthetic Enzyme Armed KillER) cells are CAR-T cells engineered to activate small-molecule prodrugs locally at tumor sites SEAKER platform is modular and can incorporate different engineered cells, antigen targets, and enzyme–prodrug combinations in vitro and in vivo proofof- concept has been established for the SEAKER approach using two different enzyme–prodrug combinations  Read more

day: Day Two

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