Ebba Sohlberg

Ebba Sohlberg

Company: Karolinska Institutet

Job title: Project Manager


ADAPT-NK – An Off-the-Shelf Allogeneic NK Cell Therapy Using Select Superdonors 2:00 pm

Using cryopreserved donor material from preselected ‘superdonors’ we developed a novel GMPcompliant NK cell expansion protocol – ADAPT-NK Superdonors were identified through selection criteria based on NK cell phenotype, as harboring large adaptive NK cell subsets with single self-KIR expression Expanded ADAPT-NK cells show strong alloreactivity in a mouse model of AML as well as…Read more

day: Day 1: Supply/Storage - Afternoon

Roundtable: How to Secure a Steady Donor Supply for a Scalable Allogeneic Product 12:30 pm

Discussing how to make truly off-the-shelf therapies a reality at large scale with a consistent supply of qualified donors Establishing multiple donor banks for generating a specific allogeneic product Exploring whether donor-derived approaches will need to be restricted to certain disease settingsRead more

day: Day 1: Manufacturing & CMC - Morning

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