Company: Nationwide Children's Hospital
Job title: Postdoctoral Fellow
Dr. Meisam Naeimi Kararoudi received his veterinary surgery degree from Iran. He obtained his PhD from the University of Perugia, Italy and was trained as an Erasmus scholar at the University of Oxford, UK. Dr. Naeimi focused on understanding the role of immune cells such as iNKT cells in cardiovascular diseases and also studied the role of miRNAs in AML using CRISPR/Cas9. During his PhD in Oxford and Italy, he received several International scholarships and grants.
Being a veterinary surgeon, immunologist and genetic engineer brought him to Sweden where he used CRISPR/Cas9 to decrease rejection after transplantation of tissue engineered organs at Sahlgrenska University Hospital. During this period, he also worked in SciLifeLab as a visiting Post-Doc to use genetic modification in cancer-related projects.
Currently, he works as a post-doc fellow in the Cell Therapy and Cancer Immunotherapy Program at Nationwide Children’s Hospital, Ohio. Under the supervision of Dr. Dean Lee, he developed a method to genetically modify the hard-to-transfect human Natural Killer cells using CRISPR, and identified novel approaches to enhance their cytotoxicity and to target cancers via chimeric antigen receptors. Dr. Naeimi is also involved in developing new methods to detect expanded NK cells in-vivo using MRI.”